Madonna

If anyone else built a song around the idea of saving the world in four minutes, we'd probably assume it was the result of a contractual obligation to some doomsday action flick. But this is the immortal Madonna. And with Timbaland marshaling a cavalry of trotting beats and synthesized brass, and General JT providing vocal reinforcement on the Mother of Reinvention's latest (hip-hop!) reincarnation, we kind of think Madge really could save the world.